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Botox Treatment For CRPS

December 1st, 2010 · 4 Comments

A recent research study looked at using botox as treatment for CRPS (RSD).

Probably best known as a wrinkle treatment, botox is also used for muscle spasm, headache, and certain pain disorders.  This study investigated botox as a treatment for CRPS, in particular looking at its effect on allodynia (excessive pain response to stimulation which shouldn’t be painful).  The study was small, with 8 participants in the double-blind section, and 6 in the open-label trial.

The results showed the botulism does not work and is painful when used in CRPS.

In the past, “negative” studies – showing something doesn’t work – were sometimes not published.  But the results of studies showing what doesn’t work can be just as useful as those showing what does.  Both kinds of information needs to reach clinicians working with patients.  If a treatment doesn’t work, it’s crucial to know that, so we don’t continue to use it.  As well, that knowledge helps researchers move on to try other new treatment, so we can make progress.

The study is:  “Botulinum Toxin A for Treatment of Allodynia of Complex Regional Pain Syndrome: A Pilot Study,” by Delaram Safarpour, Arash Salardini, Diana Richardson, and Bahman Jabbari, in Pain Medicine September 2010, Volume 11, pages 1411–1414.


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4 responses so far ↓

  • Clinic im Centrum // Dec 2, 2010 at 4:51 am

    I think that Botox doesn´t helps against headache.
    Botox cause headache!

  • dr. howard // Dec 2, 2010 at 4:18 pm

    does anyone know if medicare pays for botox treatments for chronic pain (cervical)?

  • Janet // Dec 17, 2010 at 1:39 pm

    I have found that Botulism Toxin A has been of significant help in not only stopping the spasms in my low back at the beginning of the first use approximately 9 years ago but for further damage since the car accident. It has helped with the damage caused by one Physio who forced me to JUMP and hurt my Cervical Vertebratae; It was of great help in calming the Piercing Axe that was stuck in my left eye in 2007. In 2008 I was able to cut back on the frequency of injections and then, having a fall in a handicapped Parking Spot in January of 2009, I had to return to having the shots every 8 weeks. Without the Botulism, I would have the rashes and swelling, the burning and lack of use of my left leg, my right hand and be unable to do many of the things I presently do without the Botulism. My RSD is kept to a minimum BY THE BOTULISM injections. It does make me ill for several days but by the 3rd week, I am stronger, less prone to the spasming and burning and fire shooting through my feet, hands, head and eye piercing, light sensitivity! Botox has helped me significantly. My only concern is: Doctors tell me it is SAFE and does NOT harm me at all. Please respond to let me know if this is true. I worry about what it does to my internal organs such as my liver, kidneys, heart and blood vessells.

  • Faltenbehandlung // May 9, 2011 at 5:19 pm

    It’s not so bad to have some false results during the studies. It’s worse not to publish about the mistakes. As soon as it’s found out, that the results are not real, it must be published and explained.

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