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2 New Studies Of Ketamine For Pain

October 21st, 2009 · 6 Comments

Ketamine is an anesthetic approved for both human and animal use in medical settings since 1970.  Current investigations are looking at its use for chronic pain.  2 new studies are promising:

The first study is “Ketamine produces effective and long-term pain relief in patients with Complex Regional Pain Syndrome Type 1” which appears in Pain, October 2009.  This study of 60 subjects with severe pain used an average of 4.2 days of IV Ketamine infusion.  Results showed significant decreases in pain at the end of the infusions, but no sustained decrease by 12 weeks after treatment.

This study confirms previous studies which also showed that Ketamine effectively reduces pain, but most patients need “booster” sessions to maintain pain reduction.  Unfortunately, the title of this paper is a bit misleading, as long term pain relief did not occur.

The second study is “Effects of low-dose intransal (S)-ketamine in patients with neuropathic pain” which appears in the European Journal of Pain, in press, 2009.  This study looked at the use of Ketamine administered by nose in a small sample of 16 subjects.  Pain was reduced for about 2–3 hours, with the best pain relief (30 – 40% decrease in pain) achieved at 1 hour.

These 2 studies are part of a growing body of literature supporting the use of Ketamine.  It’s a treatment that I’m warming to, but still would recommend only after more conservative measures have been tried.

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6 responses so far ↓

  • Kathy // Oct 22, 2009 at 10:23 pm

    I was very happy to see some updated information on Ketamine. I have CRPS in all my limbs. It’s also in my back from surgeries for Spinal Cord Stimulators (many that don’t work for me). Being very sensitive to medications, Ketamine would probably be my next step. My doctor doesn’t mention it much because of my sensitivity to meds. With this information it really helps me to make up my own mind.

    Thank You Very Much
    God Bless You All

  • jeisea // Oct 23, 2009 at 9:53 pm

    This treatment is well known here and with good results. I’ll pass on this post as many will be interested.

  • Michele // Nov 13, 2009 at 3:56 pm

    Thanks very much for this information. I’m currently under going the work-up proticals for the ketimine infusion. Dr. Swartzman, here in Philadelphia, PA is doing all kinds of resarch on this topic and has devoted his life to this plan of treatment. So, I am very excited to learn that there are others out there with the same kind of treatment plans, also. I really helps me to make up my mind with this extreme procedure.

    Thanks Again
    and God bless!!

  • Peggie // Nov 15, 2009 at 8:50 am

    The first time ketamine was used on me,5/08,it was injected 1st,before the oral surgeon removed all of teeth,(due to dry socket caused by ALL my pain meds for RSD.) The ketamine along with full mouth nerve blocks purpose was so I wouldn’t develop RSD in my mouth,too.Thank God it worked. I also had an ease of symptoms,(4 close 2 two mos.)after this oral surgery,w/reguard to my full body RSD.The next time I had ketamine,was during my cervical & occipital procedures in 6/09, this time I had an ease of symptoms 4 nearly 4 months. Since PA,where I live has only approved a certain dose/amount 2 be used,I was only given the legal amount in an injection. I look forward to when Ketamine can be used in my state in higher doses as in other states. This was the 1st & only thing that allowed me 2 feel almost normal 4 the 1st time in 81/2 Yrs.!!

  • Barry // May 21, 2010 at 1:18 am

    My wife has had Ketamine for chronic back and neck pain from a work related injury. It has been a massive result in her walking after 5 years of wheel chair bound and could not place her feet on the ground yet we cannot obtain the agreement of her insurance company for the use of Ketamine. Amazing! Yet it works brilliantly.

  • kristen // Nov 9, 2011 at 1:12 pm

    ketamine is dum you should have more facts about it and kaetamine is really stupid :))

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