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Medication For Pain Series 2009: Antidepressants

September 28th, 2009 · 7 Comments

Updated series:  Antidepressants

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7 responses so far ↓

  • Jeannie // Oct 5, 2009 at 3:37 pm

    How does anyone combat constipation without long term colon failure? What natural methods are there? Does anyone know? I heard there was a new anti depressant with “no constipation” side effects. If anyone knows anything about this, please email me. Thanks!

  • Ray // Nov 13, 2009 at 1:06 am


    Use a stool softener such as colace, and drink lots of water.

  • terry // Jan 21, 2010 at 2:42 pm

    Rheumatoligist decided to add Cymbalta, I had 8 days of it’s worst side effects so that is out.
    I visited a Psychiatrist to discuss taking these meds for chronic pain (“might be CRPS or RSD”) after total knee replacement. Have had the pain for over three years now, so of course I am depressed because the surgery not only did not improve my quality of life, it caused chronic pain to appear. I no longer work and have taken on the appearance and attitude of a person that is not well.
    The Psych. suggested I take Wellbutrin. Is Wellbutrin indicated for chronic pain or will it just help the depression ?

  • How to Cope with Pain // Jan 21, 2010 at 10:22 pm

    Terry, I can’t comment on your personal situation and would suggest asking your good questions to your psychiatrist.

    In general, Wellbutrin is not one of the antidepressants used commonly for pain. Regarding Cymbalta, sometimes starting with a very low dose and increasing very slowly helps make side effects manageable.

  • Bernadette // Mar 27, 2010 at 7:28 am

    Blood pressure specialist is trialling me on monoxadine to help manage high blood pressure surges associated with neuropathic pain due to CRPS Type 2. I’m also on amytriptiline 25mg, plus tramadol and gabapentin, and finding even at a low dose of monoxadine (starting 200mcg plan to increase to 400mcg) I’m having problems with the combined anti cholinergic effects. Can you suggest an SNRI as an alternative to amytriptiline to discuss with my GP? Thanks

  • How to Cope with Pain // Mar 27, 2010 at 8:26 am

    Bernadette, unfortunately I can’t make recommendations for individual readers. Your MDs should be able to decide on some alternatives.

    Good luck!

  • terry // May 5, 2010 at 1:44 pm

    Re above posting about Cymbalta:
    Yesterday my rheumatologist started me on Savella, the 2 week titration package gradually increases the dose and the directions are very clear how to take this medicine.
    The Psychiatrist maintains I should stay on the Wellbutrin as well.
    My diagnosis is now Fibromyalgia, despite the fact that I do not have the conventional fibro trigger points. We will try yet another treatment option as I press on through the 4th year of constant pain.
    I think a psych work-up before joint replacement surgery would be really important. In my case the surgeon knew I was being treated for PTSD but performed replacement surgery and subsequent arthroscopic surgery, clearly I was at risk for developing chronic pain but the surgeon did not mention anything about that, just told me to continue with my antidepressant and anxiety medicines. As I mentioned above my quality of life is seriously diminished as a result and I am now told that this type of chronic pain will never go away. At 56 that seems like many many more years like this.
    As always with another treatment plan I am optimistic, maybe Savella is the one that will work !

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